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Archive for November, 2009

Kareem news puts rare cancer in spotlight

Wednesday, November 18th, 2009

As a lifelong Philadelphia 76ers fan, I grew up rooting against Kareem Abdul-Jabbar. After all, the big, bad Lakers were always the one team blocking my beloved Sixers – led by Dr. J and company – from winning the NBA championship until “we” finally broke through in 1983, sweeping L.A. ...

Palifosfamide lacks resistance, side effects of forebears

Monday, November 16th, 2009

Cancer drugs have come a long way and work very effectively today, but they create a tremendous expense for patients because treatment requires them to be admitted to the hospital. Drugs such as doxorubicin, ifosfamide, and cyclophosphamide can have severe side effects, including brain, kidney, and bladder issues, diminishing the ...

Eyes on screen! Better biological tools sought

Wednesday, November 11th, 2009

If you’re a technology company specializing in high throughput screening and characterization of protein-based drugs, chances are the FDA wants to hear from you. Just call it part of the agency’s fact-finding mission. With biotech pursuits rapidly becoming a go-to option in mainstream drug development, FDA, like most in the ...

Acceleron looks past VEGF in cancer treatment

Friday, November 6th, 2009

Many cancer treatments being developed in the clinic focus on the VEGF pathway by blocking multiple kinase inhibitors or different proliferative agents simultaneously, which usually leads to serious side effects. But VEGF is just one piece of the tumor angiogenesis puzzle. Executives with Acceleron Pharma Inc. believe that a need exists ...

   
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